Vitapilz Agaricus im Großhandel

Applications tested in practice

Immune modulation from medicinal mushrooms


This mushroom is particularly rich in polysaccharides, which sustainably modulate the immune system. The activation of the immune system by substances in Agaricus plays a crucial role in the prevention of disorders that are generally inflammatory.


Maitake possesses huge potential for regulating the body’s own defences. Maitake contains the beta-glucan grifolan, which can increase the activity of macrophages and thus bring about targeted immune activation. *1


The polysaccharides and, specifically, certain triterpenes in Polyporus umbellatus display a strong antioxidant effect. This makes the mushroom interesting both for general immunomodulation as well as for targeted support of the defences in particularly stressful times of life.


The immune-strengthening and modulating properties of Reishi are mainly attributed to the high concentration of antioxidant beta-glucans it contains. According to studies, they can improve the proliferation of T- and B-lymphocytes and stimulate the body’s defences.

But there are many more mushrooms that can can be used for many indications associated with a weak immune system thanks to the antibacterial, antiviral and antifungal properties, the mushrooms – like Cordceps or Coriolous. 



  1. Immunomodulating Activity of Agaricus brasiliensis KA21 in Mice and in Human Volunteers, Ying Liu, Advance
    Access Publication 12 April 2007 eCAM 2008; 5(2)205–219
  2. Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts, Vaclav Vetvicka, Jana Vetvickova, Annals of Translational Medicine, Vol 2, No 2 (February 2014)
  3. Structure elucidation and immunological function analysis of a novel β-glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries, Hui Dai et.all, Glycobiology Vol. 22 No. 12 pp. 1673–1683, 2012 doi:10.1093/glycob/ cws099, Advance Access publication on June 18, 2012
  4. Immunomodulatory effect of ganoderma lucidum polysaccharides (GLP) on long-term heavy-load exercising mice., Shi Y , Cai D, Wang X, Liu X., International Journal for Vitamin and Nutrition Research. 2012 Dec; 82(6):383-90. doi: 10.1024/0300-9831/a000135.